FUNDAMENTALS OF ORAL BIOMEDICINE-口腔生物医学基础 本书特色

preface chapter ⅰ molecular regulation of tooth development and dental stem cells 001 part ⅰ　tooth development 001 part ⅱ　molecular regulation of tooth development 002 2.1 initiation of the tooth 002 2.2 bud-to-cap transition 003 2.3 condense of mesenchyme 004 2.4 enamel knot and tooth type determination 004 2.5 the homeobox code 005 2.6 hard tissue formation 006 part ⅲ dental stem cells 007 3.1 different populations of dental stem cells with diverse potential 008 3.2 tooth tissue regeneration 010 references 012 chapter ⅱ biological basis in the development and remodeling of jaws 014 introduction 014 part ⅰ　chemical composition of jaws 015 1.1 inorganic components 015 1.2 organic components 015 part ⅱ　biological basis associated with the development of jaw 016 2.1 bone development 016 2.2 processes of bone development 019 part ⅲ　biological basis associated with the remodeling of jaws 023 3.1 features of bone remodeling 023 3.2 cytological basis of bone remodeling 024 references 026 chapter ⅲ the identification of genes related to oral hereditary disease 028 part ⅰ foreword 028 1.1 the concept of medical genetics 028 1.2 the characteristics of oral and maxillofacial genetic diseases 029 part ⅱ the classification of genetic diseases 030 2.1 single-gene disease 030 2.2 mitochondrial inherited disease 030 2.3 chromosomal disease 031 2.4 polygenic disease 032 part ⅲ confirmation of pathogenic genes in mono-gene diseases 032 3.1 family pedigree analysis in mono-gene diseases 033 3.2 disease gene mapping 035 3.3 genetic polymorphism and mutation 035 part ⅳ oral genetic diseases and congenital disorders 036 4.1 genetic diseases in dental hard tissues 036 4.2 genetic diseases in periodontal tissues 039 4.3 genetic diseases in oral bone tissues 042 4.4 congenital facial cleft 043 references 050 chapter ⅳ oral ecosystem and the influential factors 053 part ⅰ ecosystem and ecology 053 1.1 oral micro-ecosystem 053 1.2 the influential factors of oral micro-ecosystem 054 part ⅱ dental plaque biofilm 057 2.1 the formation of dental plaque biofilm 058 2.2 the classification of plaque biofilm 059 2.3 the components of plaque biofilm 060 part ⅲ biofilm disease in oral cavity 060 3.1 the related microflora of dental caries 061 3.2 the related microflora of periodontal diseases 063 3.3 the progress in oral micro-ecosystem research 065 references 067 chapter ⅴ technology and application of oral tissue engineering 069 part ⅰ the concept of oral tissue engineering 069 1.1 biomaterials 069 1.2 seed cells 071 1.3 growth factors 072 part ⅱ application of tissue engineered skin and mucosa 073 2.1 tissue engineered skin 073 2.2 tissue engineered mucosa 075 partⅲ application of tissue engineered bone 076 3.1 cell sources for bone regeneration 076 3.2 growth/transcription factors for bone regeneration 076 3.3 biomaterials for bone regeneration 076 3.4 pre-clinical animal model research for bone regeneration 077 3.5 clinical translational researches for bone regeneration 078 part ⅳ future perspectives 078 4.1 strategies for neovascularization 078 4.2 strategies for osseointegration 079 4.3 strategies for tissue engineered tooth 079 references 081 chapter ⅵ characteristics and application of new dental materials 082 part ⅰ new dental filling material and their characteristics 082 1.1 dental filling materials 082 1.2 composition and properties of dental filling materials 082 part ⅱ characteristics and application of biological ceramic 084 2.1 species of biological ceramic 084 2.2 structure and properties of biological ceramics 085 part ⅲ evaluation of biocompatibility and their characteristics of nano-dental materials 086 3.1 conception of nano-dental materials 086 3.2 composition and properties of nano-dental materials 086 3.3 species of nano-dental materials 087 3.4 safety evaluation of nano-dental materials 087 part ⅳ nanometer technologies of metal implant materials 088 4.1 species of nanometer technologies of metal implant material 088 4.2 characteristics of nanometer technologies of metal implant material 089 references 089 chapter ⅶ the genetic and epigenetic alterations in oral squamous cell carcinoma 091 introduction 091 patt ⅰ genetic alterations in oral squamous cell carcinoma 092 1.1 chromosome abnormalities and microsatellite instability 092 1.2 inherited genetic gactors 096 1.3 abnormal gene and protein expression 099 1.4 somatic mutations in oscc 102 part ⅱ epigenetic alterations in oscc 102 2.1 dna methylation 102 2.2 histone modifications 104 references 105 chapter ⅷ the biological characteristics and signal pathways in oral cancer 108 part ⅰ cell proliferation and apoptosis 108 1.1 preface 108 1.2 signal transduction of cell proliferation and apoptosis 109 1.3 regulation of cancer cell proliferation and apoptosis 111 1.4 apoptosis targeted therapy in oral cancer 113 part ⅱ cell differentiation and dedifferentiation 113 2.1 concepts of cell differentiation and dedifferentiation 113 2.2 regulation mechanisms of cell di

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医学 其他临床医学 口腔科学

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