experiment 5 effects of autonomic drugs on the isolated rabbit ileum
experiment 6 the diuretic effect of furosemide on rabbits

医学机能实验学-英文版 节选

《医学机能实验学(英文版)》为机能学实验的英文教材，全书共分为五章，主要包括生理学、病理生理学、药理学实验中常见的、经典的实验内容，另外还涉及了相关的实验仪器、动物实验的基本操作技术等，内容较为详尽，图文并茂，通俗易懂。本教材可作为国内医学院校留学生机能学实验教学的教材，也可作为国内医药院校、综合性大学等相关专业学生学习机能学实验的英文教材及教师和相关人员的教学参考书。

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插图：Inbred strains can only be aquired after breeding for 20 generations continuously if starts from hybrids. After 20 generations, individual variance is very small as their genes have been purified. Inbreeding coefficient （F） is often used to represent swain purity. First generation of sibling inbreeding can reduce heterozygosis by 19%, which means homozygosis is increased by 19%. Inbreeding coefficient could reach 98.6% in theory within 20 generations However, more methods to examine the genetic homozygosis are needed to determine strain purity in addition to inbreeding coefficient. Inbred strains are used to be called 'pure strains'. There have been 250 inbred strains for albino mice till 1980. Development of inbred strains for experimental animals like albino rats and albino mice have greatly promoted biological and medical experimental research, especially tumor research.（2） Mutant strains: Mutant strains can be established by mutation of individual gene, introduction of certain gene or multiple backcross to keep the genetic features. These individuals have same genetic defect or pathosis, such as dwarf, atrichia, obesity, amyotrophy, caligo lentis and retina degeneration.Currently avaible mutant strains with certain diseases are listed: anaemia mouse, tumor mouse, leukaemia mouse, diabetic mouse, hypertension mouse and athymic mouse, etc.（3） F1 hybrid: The first generation offsprings of two inbred strains is called F1 hybrid. It has both the features of inbred strains and the hybrid ascendancy. F1 hybrid has merits like vigorous vitality, high reproductive rate, fast growth, strong body constitution and disease resistance. It has same experimental effects as inbred animals. F1 hybrid is also call systemic hybrid animals.（4） Closed population: It is the population relatively maintaining the same blood relationship developed by random breeding within one strain for mo

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